Search details
1.
Energetic Trade-Offs and Hypometabolic States Promote Disease Tolerance.
Cell
; 177(2): 399-413.e12, 2019 04 04.
Article
in English
| MEDLINE | ID: mdl-30853215
2.
Perinatal Licensing of Thermogenesis by IL-33 and ST2.
Cell
; 166(4): 841-854, 2016 Aug 11.
Article
in English
| MEDLINE | ID: mdl-27453471
3.
Perinatal Licensing of Thermogenesis by IL-33 and ST2.
Cell
; 171(7): 1707, 2017 12 14.
Article
in English
| MEDLINE | ID: mdl-29245014
4.
Discovery of 1-[2-(1-methyl-1H-pyrazol-5-yl)-[1,2,4]triazolo[1,5-a]pyridin-6-yl]-3-(pyridin-4-ylmethyl)urea as a potent NAMPT (nicotinamide phosphoribosyltransferase) activator with attenuated CYP inhibition.
Bioorg Med Chem Lett
; 43: 128048, 2021 07 01.
Article
in English
| MEDLINE | ID: mdl-33887438
5.
Discovery of DS68702229 as a Potent, Orally Available NAMPT (Nicotinamide Phosphoribosyltransferase) Activator.
Chem Pharm Bull (Tokyo)
; 69(11): 1110-1122, 2021.
Article
in English
| MEDLINE | ID: mdl-34719594
6.
Synthesis and biological evaluation of novel imidazol-1-ylacetic acid derivatives as non-brain penetrant bombesin receptor subtype-3 (BRS-3) agonists.
Bioorg Med Chem Lett
; 26(17): 4205-10, 2016 09 01.
Article
in English
| MEDLINE | ID: mdl-27491709
7.
Synthesis and biological evaluation of novel chiral diazepine derivatives as bombesin receptor subtype-3 (BRS-3) agonists incorporating an antedrug approach.
Bioorg Med Chem
; 23(1): 89-104, 2015 Jan 01.
Article
in English
| MEDLINE | ID: mdl-25497965
8.
Identification of the 5,5-dioxo-7,8-dihydro-6H-thiopyrano[3,2-d]pyrimidine derivatives as highly selective PDE4B inhibitors.
Bioorg Med Chem Lett
; 24(3): 893-9, 2014 Feb 01.
Article
in English
| MEDLINE | ID: mdl-24412069
9.
Discovery of novel chiral diazepines as bombesin receptor subtype-3 (BRS-3) agonists with low brain penetration.
Bioorg Med Chem Lett
; 24(3): 750-5, 2014 Feb 01.
Article
in English
| MEDLINE | ID: mdl-24412111
10.
Identification of the fused bicyclic 4-amino-2-phenylpyrimidine derivatives as novel and potent PDE4 inhibitors.
Bioorg Med Chem Lett
; 23(11): 3325-8, 2013 Jun 01.
Article
in English
| MEDLINE | ID: mdl-23602400
11.
Synthesis and biological evaluation of 5-carbamoyl-2-phenylpyrimidine derivatives as novel and potent PDE4 inhibitors.
Bioorg Med Chem
; 21(22): 7025-37, 2013 Nov 15.
Article
in English
| MEDLINE | ID: mdl-24094436
12.
Evaluation of the therapeutic index of a novel phosphodiesterase 4B-selective inhibitor over phosphodiesterase 4D in mice.
J Pharmacol Sci
; 123(3): 219-26, 2013.
Article
in English
| MEDLINE | ID: mdl-24152964
13.
DS-5670a, a novel mRNA-encapsulated lipid nanoparticle vaccine against severe acute respiratory syndrome coronavirus 2: Results from a phase 2 clinical study.
Vaccine
; 41(38): 5525-5534, 2023 08 31.
Article
in English
| MEDLINE | ID: mdl-37586958
14.
A splice-switching oligonucleotide treatment ameliorates glycogen storage disease type 1a in mice with G6PC c.648G>T.
J Clin Invest
; 133(23)2023 Dec 01.
Article
in English
| MEDLINE | ID: mdl-37788110
15.
Inhibition of neutrophil migration in mice by mouse formyl peptide receptors 1 and 2 dual agonist: indication of cross-desensitization in vivo.
Immunology
; 132(3): 441-50, 2011 Mar.
Article
in English
| MEDLINE | ID: mdl-21039475
16.
Formyl peptide receptor 1 and 2 dual agonist inhibits human neutrophil chemotaxis by the induction of chemoattractant receptor cross-desensitization.
J Pharmacol Sci
; 115(1): 63-8, 2011.
Article
in English
| MEDLINE | ID: mdl-21173551
17.
The pyrazolone originally reported to be a formyl peptide receptor (FPR) 2/ALX-selective agonist is instead an FPR1 and FPR2/ALX dual agonist.
J Pharmacol Sci
; 111(3): 317-21, 2009 Nov.
Article
in English
| MEDLINE | ID: mdl-19926937
18.
Naive CD4+ T cells exhibit distinct expression patterns of cytokines and cell surface molecules on their primary responses to varying doses of antigen.
J Immunol
; 168(7): 3242-50, 2002 Apr 01.
Article
in English
| MEDLINE | ID: mdl-11907078
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